Mass Production of Medicinal Plants for Obtaining Secondary Metabolite Using Liquid Mediums Via Bioreactor Systems: SETISTM And RITA®

  • Ergun KAYA
  • Selin GALATALI
  • Sevinc GULDAG
  • Bilge OZTURK
  • Muammer CEYLAN
  • Onur CELIK
  • Irem AKTAY
Keywords: Micropropagation, plant breeding, plant clonal propagation, TIS


Micropropagation techniques provide effective and important ways for plant mass propagation. While some cultivated species are still accepted
as comparatively resistant to tissue culture, there are a lot of successful applications of somatic and zygotic embriyogenesis, organaogenesis,
micropropagation have been reported from different type of plant species. In vitro liquid culture systems are thought to be more efficient than
semi-solid culture systems because of having great advantages of them such as successful automation, big mass production, easy handling,
simple calibration of medium components and culture conditions. Temporary immersion bioreactor systems (TIS) based on liquid medium
usage have been provided many utilities such as reduction of production cost and higher proliferation rate. This review aimed to describe
advantages of micropropagation protocols developed using two different temporary immersion bioreactor systems, SETISTM and RITA®