Tümör Nekroz Faktör ve Servikal Kanser Bağlantısı

Abstract

Tumor necrosis factor (TNF), which causes tumor necrosis, is a cytokine that also plays role of infl ammation
and apoptosis processes. TNF, secreted priorly by macrophage any many other cells in reactions such as allergy
and infl ammation, plays essential roles in innate immunity. The latest works indicate that while TNF induces
tumor necrosis for example cervical tumors, it also increases to tumor growth. It is reported that a decrease in
TNF secretion causes the development of cancer cells whereas an increase in TNF secretion leads to apoptosis
or necrosis. This review is planned in order to clarify the biological activities of TNF and its relationship with
cervical tumors.