Alzheimer Hastalığında Moleküllerin Rolü
Özet Görüntüleme: 41 / PDF İndirme: 161Anahtar Kelimeler:
Alzheimer disease, Tau tangles, Amyloid peptide, Amyloid plaques.Özet
Alzheimer that indicate with mental defects is usually late on pretreatment application for perceiving a
geriatric problem. Many factors cause to defects that damaged neurons transmissions on brain. For examples;
virus, chemical messengers, proteins, genes, carbohydrates and calcium metabolism, environmental factors etc.
This case in terms of molecular aspect is involved with proteins. These protein aggregations that developed into
neurons and among them, are attracted attention. This aggregation occurring into cells is resulted in constituting
neurofi brillary balls of tau protein and damaging structure and function of cell through bounding to tubulin
protein on microtubules structure. Whereas, constructions called amyloid plaques (β-amyloid peptide) among
neurons show an arrangement that point out also dementia intensity.
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Telif Hakkı (c) 2008 Türk Bilimsel Derlemeler Dergisi
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